Safety Profile

What to
Look for

Some DUPIXENT patients may experience side effects. It is important to know what to expect and watch out for.

This website is not intended to be a substitute for medical advice. Please refer to the Patient Information Leaflet in the pack for full safety information.

What are the possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Dupixent can cause serious side effects, including very rare allergic reactions. The signs of allergic reaction may include, breathing problems, swelling of the face, lips, mouth or tongue, fainting, dizziness, feeling lightheaded, fever, feeling unwell, swollen lymph nodes, hives, itching, joint pain or skin rash.

  • Very Common
    (may affect more than 1 in 10 people):

    Injection site reactions (such as redness, swelling, and itching)
  • Common
    (may affect up to 1 in 10 people):

    Headache, eye dryness, redness and itching, eyelid itching, redness and swelling, eye infection, and cold sores (on lips and skin)
  • Uncommon
    (may affect up to 1 in 100 people):

    Inflammation of the eye surface, sometimes with blurred vision (keratitis, ulcerative keratitis).

Reporting of side effects

Dupixent is subject to additional monitoring. This will allow quick identification of new safety information. If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard.

By reporting side effects, you can help provide more information on the safety of this medicine.

What should I watch out for before taking Dupixent?

Precautions
Do not use Dupixent if you are or think you are allergic to dupilumab or any of the other ingredients of this medicine. If you think you may be allergic, or you are not sure, ask your healthcare professional for advice before using this medicine.

Pregnancy and breast-feeding
If you're pregnant, think you may be pregnant, or are planning to have a baby, ask your healthcare professional for advice before using this medicine. The effects of this medicine in pregnant women are not known; therefore, it is preferable to avoid the use of Dupixent in pregnancy unless your healthcare professional advises to use it. If you are planning to breast-feed, you and your healthcare professional should decide if you will breast-feed or use this medicine. You should not do both.

Allergic reactions
Very rarely, Dupixent can cause serious side effects, including allergic (hypersensitivity) reactions. You must look out for signs of these conditions such as breathing problems, swelling of the face, mouth and tongue, fainting, dizziness, feeling lightheaded (low blood pressure), fever, general ill feeling, swollen lymph nodes, hives, itching, joint pain, skin rash while you are taking this medicine. Stop using this medicine and tell your healthcare professional or get medical help immediately if you notice any signs of an allergic reaction.

Eosinophilic conditions
Rarely patients taking an asthma medicine may develop inflammation of blood vessels or lungs due to an increase of certain white blood cells (eosinophilia). Tell your doctor immediately if you develop a combination of symptoms such as a flu-like illness, pins and needles or numbness of arms or legs, worsening of pulmonary symptoms, and/or rash.

Parasitic (intestinal parasites) infection
Dupixent may weaken your resistance to infections caused by parasites. If you already have a parasitic infection, it should be treated before you start treatment with this medicine. Check with your healthcare professional if you have diarrhoea, gas, upset stomach, greasy stools, and dehydration which could be a sign of a parasitic infection. If you live in a region where these infections are common or if you are travelling to such a region, check with your healthcare professional.

Eye problems
Talk to your healthcare professional if you have any new or worsening eye problems, including eye pain or changes in vision.

Vaccinations
Talk to your healthcare professional if you have recently had or are due to have a vaccination.

F.A.Qs

Find out more about Dupixent dosage, storage, and more.

DUPIXENT MyWay

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