What to
Look for

What to tell your Healthcare Professional

Allergic reactions
Very rarely, Dupixent can cause serious side effects, including allergic (hypersensitivity) reactions. You must look out for signs such as:

• fever
• general ill feeling
• swollen lymph nodes
• hives
• itching
• joint pain
• skin rash

Stop using Dupixent and tell your healthcare professional or get medical help immediately if you notice any signs of an allergic reaction.

Parasitic (intestinal parasites) infection
Dupixent may weaken your resistance to infections caused by parasites. If you already have a parasitic infection it should be treated before you start treatment with this medicine.

Talk to your healthcare professional if you have any of the following signs of a parasitic infection, such as:

• diarrhea
• gas
• upset stomach
• greasy stools
• dehydration

If you are planning to travel to or have lived in a region where these infections are common, please speak to your healthcare professional.

Asthma
If you have asthma and are taking medicines for asthma, do not change or stop your asthma medicine without talking to your healthcare professional. Talk to your healthcare professional before you stop Dupixent.

Eye problems
Tell your healthcare professional if you have any new or worsening eye problems, including:

• eye dryness, redness and itching
• eyelid itching, redness and swelling
• eye infection
• eye pain or changes in vision

Anyone involved in your healthcare should know you have been prescribed Dupixent
In order for your healthcare professionals to make the most informed decisions about your health it is important that they know all the medicines you are taking, including Dupixent.

Tell your healthcare professional:

• if you are using, have recently used, or might use any other medicines
• if you have recently had or are due to have a vaccination

Pregnancy and breast-feeding
Talk to your healthcare professional before using Dupixent if you are pregnant, think you may be pregnant, or are planning to have a baby. The effects of this medicine on pregnant women and/ or unborn babies are not known. Therefore it is preferable to avoid the use of Dupixent in pregnancy unless your healthcare provider advises you to do it.

Talk to your healthcare provider before using Dupixent if you are breast feeding or are planning to breast-feed. You and your healthcare professional should decide if you will breast-feed or use Dupixent. You should not do both.

Driving and using machines
The use of Dupixent is not expected to affect your ability to drive or use machines. However, if you are feeling tired or unwell after you use Dupixent, you should not drive or use machines.

Sodium content
Dupixent is essentially "sodium free" as it contains less than 1 mmol of sodium (23 mg) per 300 mg dose.